GLP-1 medication articles and explainers
Plain-English explainers about the GLP-1 medicines available to UK patients — how they work, what the trials found, and where UK licensing honestly stands. Every article is information only: we do not sell medicines, recommend suppliers, or give medical advice.
New to these medicines? Start with the main guides — Mounjaro (tirzepatide), Wegovy (semaglutide), the Wegovy pill and Foundayo (orforglipron) — or the side-by-side GLP-1 medication comparison and the FAQ. The articles below each take one question further.
GLP-1 medicines and pregnancy: what the UK product information says
GLP-1 and pregnancy: what the Mounjaro, Wegovy, Wegovy pill and Foundayo SmPCs say about stopping before conceiving, the pill and breastfeeding.
What a UK online consultation for GLP-1 medicines involves
GLP-1 online consultation UK: what GPhC guidance says it should include for Mounjaro, Wegovy, the Wegovy pill or Foundayo, and how to check a pharmacy.
GLP-1 medicines and surgery: what to tell your anaesthetist
GLP-1 medications before surgery: why Mounjaro, Wegovy, the pill and Foundayo matter to your anaesthetist, who decides on pausing, and what to tell the team.
GLP-1 medications: what is known about long-term safety
GLP-1 long-term safety: how long the Wegovy, Mounjaro and Foundayo trials ran, the known serious risks, what is still studied and why reporting matters.
Tirzepatide vs semaglutide: the difference explained
Tirzepatide vs semaglutide: how Mounjaro's dual GIP/GLP-1 molecule differs from Wegovy and Ozempic on dosing, the SURMOUNT-5 head-to-head and UK licences.
GLP-1 for diabetes vs weight loss: same drugs, different rules
GLP-1 for diabetes vs weight loss in the UK: why Ozempic, Rybelsus and Wegovy share a molecule but differ on licence, eligibility, dose ladder and NHS route.
What Happens When You Stop a GLP-1 Medicine? What the Trials Show
Stopping GLP-1 medication: what happens to appetite, weight and blood sugar, what the SURMOUNT-4 and STEP trials found, and why to plan it with a prescriber.
How Do GLP-1 Drugs Actually Cause Weight Loss? The Mechanism Explained
How do GLP-1 drugs cause weight loss? What Mounjaro, Wegovy, the Wegovy pill and Foundayo do to appetite, fullness, stomach emptying and blood sugar.
GLP-1 Medications and Muscle Loss: What the Evidence Shows
Do GLP-1 medications cause muscle loss? What the Mounjaro, Wegovy and Foundayo body-composition studies found, and how strength work and protein may help.
GLP-1 Tablets vs Injections in the UK: What the Oral Options Actually Change
GLP-1 tablets vs injections in the UK: how the Wegovy pill and Foundayo differ from the weekly Mounjaro and Wegovy jabs on routine, dose ladders and trial results.
Who Is Eligible for GLP-1 Treatment in the UK? NHS and Private Rules
Who can get Mounjaro, Wegovy, the Wegovy pill or Foundayo in the UK? Licence BMI rules, NHS England criteria and who should avoid them, as of September 2026.
Managing GLP-1 Side Effects: Nausea, Constipation and Tiredness
How to manage common GLP-1 side effects such as nausea, constipation and tiredness on Mounjaro, Wegovy or the tablets, and which symptoms need urgent help.
GLP-1 Medications Compared UK: Mounjaro, Wegovy, the Pill & Foundayo
An impartial UK comparison of GLP-1 medications — Mounjaro, Wegovy, the Wegovy pill and Foundayo. How they differ on weight loss, dosing, side effects and access.
What Are GLP-1 Medications? How the Class Works
What are GLP-1 medications? A plain-English UK guide to how this class of weight-loss and diabetes medicines works, the main options, and who they suit.